Which of the following best describes endocrine disruptors?

Endocrine disruptors are best defined as chemicals that interfere with hormonal systems. These substances can mimic hormones, block the effects of hormones, or cause the body to produce more or less of a hormone than normal. By disrupting the communication between hormones and their receptors, they can alter physiological processes in both humans and wildlife, leading to various health issues, including reproductive problems, developmental disorders, and increased risks of certain cancers.

The other options do not accurately reflect the nature of endocrine disruptors. For example, chemicals that enhance hormonal systems would imply that these substances support normal hormone function rather than interfering with it. Substances that have no effect on hormones would not fall under the category of endocrine disruptors, as these are defined specifically by their impact on hormonal regulation. Lastly, claiming that only natural substances regulate hormones narrows the definition inappropriately, as endocrine disruptors can be synthetic or natural and may have harmful effects on hormonal activity rather than serving a regulatory function. Thus, the correct descriptor is that these chemicals interfere with hormonal systems.